Download ebook Influence of Piperin on Pioglitazone Metabolism and Pk/Pd : Diabetes
Download ebook Influence of Piperin on Pioglitazone Metabolism and Pk/Pd : Diabetes

Influence of Piperin on Pioglitazone Metabolism and Pk/Pd : Diabetes by Rajitha Koppula

Influence of Piperin on Pioglitazone Metabolism and Pk/Pd : Diabetes
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Author: Rajitha Koppula
Page Count: 80 pages
Published Date: 03 Aug 2014
Publisher: LAP Lambert Academic Publishing
Publication Country: United States
Language: English
ISBN: 9783659553011
File size: 32 Mb
Download Link: Influence of Piperin on Pioglitazone Metabolism and Pk Pd Diabetes
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Several factors directly or indirectly influence the CYP activity. CYP mediated metabolism are likely to be potential candidates for drug interaction.Many drug interactions are a result of induction or inhibition of CYP enzymes. Herbal medicines that modulate intestinal and hepatic CYPs can alter the bioavailability and clearance of co -administered drugs. The diabetic patients have reduced immune system where as Piperine which have significant immunomodulatory activity. Hence, the combination has a beneficial effect in diabetic condition in view of the side effects of pioglitazone.Hence, the combination has a beneficial effect in diabetic condition, but special concern has to be observed in diabetic patients with cardiovascular complications in view of the side effects of pioglitazone. Hence the present investigation warrants further studies to find out the relevance of this interaction in human beings and postulates the exact mechanism involved.

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